PDGF and Microneedling

(Platelet- Derived Growth Factor)

PLATELET derived growth factor

Clinically Proven Regenerative Power

At Pure Med Spa we offer Ariessence Pure PDGF+ a revolutionary skin rejuvenation treatment—the first and only aesthetic product to feature an FDA-approved growth factor. It combines platelet-derived growth factor (PDGF) with hyaluronic acid to deliver powerful regenerative results, helping our patients achieve visibly healthier, more youthful skin.

Platelet-Derived Growth Factor (PDGF) is a naturally occurring protein found in human blood, platelets, embryonic tissues, and bone. It plays a critical role in cellular growth, tissue repair, and wound healing. PDGF is essential for stimulating the activity of:

·         Stem cells

·         Fibroblasts

·         Smooth muscle cells

·         New blood vessel formation

·         Collagen and elastin synthesis

·         Extracellular matrix production (including glycosaminoglycans and hyaluronic acid)

TREATMENT OPTIONS

Ariessence

Clinically Proven Regenerative Power

Recombinant PDGF—a lab-engineered version of the natural protein—has been used therapeutically for over 15 years in more than 5 million patients in fields such as orthopedic and maxillofacial surgery. Its safety and effectiveness in promoting healing are well-established.

Histological studies show that wounds treated with pure PDGF exhibit:

  • Fewer inflammatory cells

  • Increased collagen production

  • Enhanced blood supply

  • Improved skin architecture and elasticity

    Why Ariessence?

    Unlike platelet-rich plasma (PRP), which is derived from a patient’s blood and varies in quality, Ariessence® Pure PDGF+ offers:

    • Standardized, pharmaceutical-grade purity

    • No human or animal-derived components

    • Consistent and predictable results

    • Minimal risk of allergic reactions


Results

KEY BENEFITS

  • Faster Healing: PDGF shortens downtime by supporting rapid tissue repair.

  • Smoother Texture & Radiance: Visibly improves fine lines, pores, and overall skin tone.
    Boosted Collagen & Elasticity: Amplifies the skin-firming effects of microneedling.

  • Safe & Non-Immunogenic: Lab-derived growth factor ensures consistency and purity—no blood draw, no risk of allergic reaction. Scar Treatment

  • Reversing Sun Damage

  • Reversing Hyperpigmentation

  • Stretch Marks

  • Skin Elasticity

BENEFITS

  • Non-surgical, minimally-invasive treatment

  • Same Day Procedure

  • Zero Downtime

  • FDA-approved

  • Minimal side effects

  • Start seeing results a week after treatment

  • Regenerates natural collagen

WHAT OUR PATIENTS ARE SAYING

I was very hesitant to get Botox. They really listened to me and created a plan for my goals and budget. I'm so happy I became a patient at Pure Med Spa and I was able to get rid of those crows feet around my eyes and forehead! It is great to look in the mirror and see a younger me! Next we do my lips!

Savannah d. / sausalito

Melissa is THE BEST. She listens, advises, and works with the precision of a surgeon. She's also thoughtful and caring. The office is beautiful and parking is easy. I simply could not recommend more!

Lora l. / san jose

At Pure Med Spa I have had 4 micro-needling treatments with PRF and my skin has never looked better. It was pain free with numbing cream and my skin is still looking great. I have found my stay younger secret and I am hooked! I highly recommend Pure Med Spa. Thank​ you so much​!

belinda s. / san jose

Pricing Packages

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PRP Hair

$ 13 /unit

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PRP/PRF Facial

$ 800

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Vampire Facial

$ 850

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FREQUENTLY ASKED QUESTIONS

What happens when you have a PRP or PRF Treatment?

Plasma is a component of our blood and contains proteins which help the blood to clot and support cell growth. Platelets are found within the blood and are responsible for recognizing and repairing damaged cells by forming a plug, or clot. PRP Treatments use the body’s own healing processes to rejuvenate the skin and promote new cell growth.

During treatment, a member of our experienced and trained staff will draw blood from your arm. The small vial of blood will be placed and spun in a centrifuge to separate the red blood cells from the plasma. The PRP-platelet rich plasma or PRF- platelet rich fibrin is then applied topically with microneedling or injected into the skin or scalp for treatment. PRP/PRF have been shown to help fade darkness under eyes, provide natural facial volume restoration, and even help with hair loss when injected in to the scalp.

What is PRF (Platelet Rich Fibrin?)

Platelet-Rich Fibrin (PRF) which is a complex Fibrin Matrix rich in Platelets, Leukocytes and Mesenchymal stem cells. For 10-12 days this results in the constant release of growth factors and interleukins which accelerate tissue healing and regenerating processes.

This 100% autologous rejuvenation technique is a substantial progress from the well-established PRP (or Platelet-Rich Plasma) technique where growth factors are all released only for a few minutes after treatment. This is all natural. There is no coating, additive or anticoagulant present in the tubes and it is proven to release a higher concentration of growth factors for a longer period of time. In Cosmetic surgery, PRF is used to accelerate the wound healing process and reduces scarring.

Pre-care Instructions and Relative Contraindications:

This treatment is highly dependable on the level of hydration of the patient (patients need to start hydration process 72 hours before treatment). Patients who smoke may have less response to this treatment.PRF is effective in most cases; no guarantees can be made that a specific patient will benefit from this procedure which is why a consultation is so important.

Additionally, the nature of cosmetic procedure may require a patient to return for numerous visits in order to achieve the desired results or to determine whether PRF may not be completely effective at treating the particular condition. The average patient needs about 3-4 treatment sessions separated by 4-6 weeks and the final result won’t be readily visible for 4-9 months.